Head of rugby Paul Gustard believes Mark Lambert’s “milestone moment” will spur his Harlequins side on against leaders Exeter Chiefs at The Stoop on Saturday (3pm).

Sixteen years after making his debut the 35-year-old prop will run out for the 250th time in Quins colours.

Scrum-half Danny Care will also make a landmark outing this weekend as he plays his 275th game for the London club.

Gustard heralded the duo as “two of Quins’ all-time greats” and hopes to mark their special day with a Gallagher Premiership victory.

“On Saturday we get to celebrate another milestone moment with Mark Lambert making his 250th run-out for Harlequins,” Gustard said.

“Likewise, Danny Care will be making his 275th Quins appearance.

“Lamby and DC, are two of Quins’ all-time greats and the sheer number of games they have played for the Quarters is testament to their talent and perseverance.

“It is a phenomenal achievement for Lamby to reach this amount of games at the coal face of rugby especially when we consider how he manages his rugby with his work with our excellent Foundation.

“I know the squad will be motivated to perform for the big man and make sure he has a positive memory of Saturday.”

Lock Matt Symons returns to the starting line-up having recovered from injury while fit-again wing Ross Chisholm replaces the injured Cadan Murley.

New Zealand centre Francis Saili is named among the replacements having missed a large portion of the season through injury and Gustard is excited to see him in action.

“Like all, but a couple of teams this year, we have struggled with consistency with a primary factor being down to the number of injured players currently in the squad,” Gustard said.

“Last week we added two more contact injuries to the medical room in Cadan Murley and Santiago Garcia Botta which presents opportunity for others.

“We are however delighted to have the likes of Matt Symons and Ross Chisholm return from injury as well as Francis who will look to add some magic after a lengthy spell on the sidelines.”

Exeter are eight points clear at the top of the table and were in ruthless form when they thrashed Northampton Saints 57-7 last weekend.

Ninth-placed Quins have lost their past two matches with their last win coming against Chiefs in the Premiership Rugby Cup semi-finals earlier this month.

“We have had a couple of close games in the last two weeks, with results going against us,” Gustard added.

“But we have seen positive signs and progress from what is largely a young side that is still developing.

“We have worked hard this week to implement some tactical variation and look to challenge the league leaders both sides of the ball.”